Article
Dynamic regulation of Cdr1 kinase localization and phosphorylation during osmotic stress.
The Journal of biological chemistry - 10 Nov 2017
Opalko Hannah E, Moseley James B
Abstract excerpt
Environmental conditions modulate cell cycle progression in many cell types. A key component of the eukaryotic cell cycle is the protein kinase Wee1, which inhibits the cyclin-dependent kinase Cdk1 in yeast through human cells. In the fission yeast Schizosaccharomyces pombe, the protein kinase Cdr1 is a mitotic inducer that promotes mitotic entry by phosphorylating and inhibiting Wee1. Cdr1 and Wee1 both localize...
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