Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Risk Factors for Autoimmune Thyroid Disease might Affect the Susceptibility to and Modulate the Progression of Primary Biliary Cholangitis.

Journal of gastrointestinal and liver diseases : JGLD - 1 Sept 2017

Kuś Aleksander, Arłukowicz-Grabowska Magdalena, Szymański Konrad, Wunsch Ewa, Milkiewicz Małgorzata, Płoski Rafał, Shums Zakera, Norman Gary L, Milkiewicz Piotr, Bednarczuk Tomasz, Krawczyk Marcin

Abstract excerpt

BACKGROUND AND AIMS: Patients with primary biliary cholangitis (PBC) frequently suffer from extrahepatic autoimmune conditions, of which autoimmune thyroid disease (AITD) is one of the most common. Previous studies identified several genetic variants increasing the odds of developing AITD. Here we investigate whether AITD-associated polymorphisms might also play a role in the development and clinical course of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross-Sectional Studies

Share to Disease Progression

Share to Genetic Association Studies

Share to Liver Cirrhosis, Biliary

Share to Odds Ratio

Share to Thyroiditis, Autoimmune

Source

Identifiers

PMID: 28922436
DOI: 10.15403/jgld.2014.1121.263.kus

Genes

MMEL1
PTPN22
CTLA4
RNASET2
TPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Risk Factors for Autoimmune Thyroid Disease might Affect the Susceptibility to and Modulate the Progression of Primary Biliary Cholangitis.PMID 28922436Read ↗

Genetic link between primary biliary cholangitis and extrahepatic autoimmune diseases: A bidirectional two-sample Mendelian randomization studySemantic proximity Read ↗

CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis.Semantic proximity Read ↗

The immunogenetics of primary biliary cirrhosis: A comprehensive review.Semantic proximity Read ↗

Genetics and epigenetics in the pathogenesis of primary biliary cholangitis.Semantic proximity Read ↗

The Causal Effects of Primary Biliary Cholangitis on Thyroid Dysfunction: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

The Pathogenesis of Autoimmune Liver Disease.Semantic proximity Read ↗

The genetic architecture of primary biliary cholangitis.Semantic proximity Read ↗

Genetic architecture of primary biliary cholangitis: strong evidence for HLA and non-HLA risk lociSemantic proximity Read ↗

Genetic Contribution to the Pathogenesis of Primary Biliary Cholangitis.Semantic proximity Read ↗

Dissecting causal relationships between primary biliary cholangitis and extrahepatic autoimmune diseases based on Mendelian randomization.Semantic proximity Read ↗

Dissecting causal relationships between primary biliary cholangitis and extrahepatic autoimmune diseases based on Mendelian randomizationSemantic proximity Read ↗

Genetic and familial considerations of primary biliary cirrhosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.