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Article

Characterization of enhancers and the role of the transcription factor KLF7 in regulating corneal epithelial differentiation.

The Journal of biological chemistry - 17 Nov 2017

Klein Rachel Herndon, Hu William, Kashgari Ghaidaa, Lin Ziguang, Nguyen Tuyen, Doan Michael, Andersen Bogi

Abstract excerpt

During tissue development, transcription factors bind regulatory DNA regions called enhancers, often located at great distances from the genes they regulate, to control gene expression. The enhancer landscape during embryonic stem cell differentiation has been well characterized. By contrast, little is known about the shared and unique enhancer regulatory mechanisms in different ectodermally derived epithelial...

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Topics

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Share to Acetylation
Share to Chromatin Immunoprecipitation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Corneal Diseases

Share to Enhancer Elements, Genetic

Share to Epithelium, Corneal

Share to Histones

Share to Kruppel-Like Factor 4

Share to Kruppel-Like Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 28916725
DOI: 10.1074/jbc.M117.793117
PMCID: PMC5704477

Genes

KLF7
KLF4
KLF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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