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Article

Overcoming Insulin Insufficiency by Forced Follistatin Expression in β-cells of db/db Mice.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 May 2015

Zhao Chunxia, Qiao Chunping, Tang Ru-Hang, Jiang Jiangang, Li Jianbin, Martin Carrie Bette, Bulaklak Karen, Li Juan, Wang Dao Wen, Xiao Xiao

Abstract excerpt

Diabetes poses a substantial burden to society as it can lead to serious complications and premature death. The number of cases continues to increase worldwide. Two major causes of diabetes are insulin resistance and insulin insufficiency. Currently, there are few antidiabetic drugs available that can preserve or protect β-cell function to overcome insulin insufficiency in diabetes. We describe a therapeutic...

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PMID: 25676679
DOI: 10.1038/mt.2015.29
PMCID: PMC4427879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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