Article
Pneumococcal 23B Molecular Subtype Identified Using Whole Genome Sequencing.
Genome biology and evolution - 1 Aug 2017
Kapatai Georgia, Sheppard Carmen L, Troxler Lukas J, Litt David J, Furrer Julien, Hilty Markus, Fry Norman K
Abstract excerpt
The polysaccharide capsule is a major virulence factor of Streptococcus pneumoniae and the target of all currently licensed pneumococcal vaccines. At present, there are 92 serologically distinct pneumococcal serotypes. Structural and antigenic variation of capsular types is the result of genetic variation within the capsular polysaccharide synthesis (CPS) locus; however, genetic variation may not always result in...
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