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Article

Pneumococcal genotype 23B1 as a driver of increased 23B serotype carriage, penicillin non-susceptibility, and invasive disease in Belgium: a retrospective analysis.

Journal of clinical microbiology - 9 Apr 2025

Dierckx Lara, Rodriguez-Ruiz Juan Pablo, Ekinci Esra, van Heirstraeten Liesbet, Willen Laura, Cuypers Lize, Beutels Philippe, Maertens Kirsten, Desmet Stefanie, Theeten Heidi, Malhotra-Kumar Surbhi

Abstract excerpt

Streptococcus pneumoniae serotype 23B, a non-vaccine serotype, has shown an increasing prevalence and penicillin non-susceptibility among carriage and invasive pneumococcal disease (IPD) isolates. Recently, a novel penicillin non-susceptible genotype has emerged, named 23B1. In the framework of the Belgian pneumococcal carriage study, we studied the prevalence of 23B0/23B1 among 586 23B strains (2016-2022) in 172...

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PMID: 40071954
DOI: 10.1128/jcm.01696-24
PMCID: PMC11980397

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