Article
Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing.
PloS one - 1 Jan 2017
Demczuk Walter H B, Martin Irene, Hoang Linda, Van Caeseele Paul, Lefebvre Brigitte, Horsman Greg, Haldane David, Gubbay Jonathan, Ratnam Sam, German Gregory, Daley Bernier Jennifer, Strudwick Lori, McGeer Allison, Zhanel George G, Van Domselaar Gary, Graham Morag, Mulvey Michael R
Abstract excerpt
Since implementation of the 13-valent polyvalent conjugate vaccine (PCV13) in Canada during 2010, the proportion of PCV13 serotypes causing invasive pneumococcal disease (IPD) has declined from 55% (n = 1492) in 2010 to 31% (n = 764) in 2014. A concurrent increase of non-PCV13 serotypes has occurred and 22F has become the most prevalent serotype in Canada increasing from 7% (n = 183) to 11% (n = 283). Core single...
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