Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cost-effective screening of DNMT3A coding sequence identifies somatic mutation in pediatric T-cell acute lymphoblastic leukemia.

European journal of haematology - 1 Dec 2017

Szarzyńska-Zawadzka Bronisława, Kosmalska Maria, Sędek Łukasz, Sonsala Alicja, Twardoch Magdalena, Kowalczyk Jerzy R, Szczepański Tomasz, Witt Michał, Dawidowska Małgorzata

Abstract excerpt

BACKGROUND AND OBJECTIVES: In pediatric T-cell acute lymphoblastic leukemia (T-ALL), risk assignment schemes preclude reliable prediction of outcome, and thus, new prognostic factors are needed. Mutations in DNMT3A are candidate prognostic and classification markers in adults with acute myeloid leukemia (AML) and T-ALL and thus were considered as candidates prognostic markers in pediatric T-ALL. PATIENTS AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Cost-Benefit Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA (Cytosine-5-)-Methyltransferases

Share to DNA Methyltransferase 3A

Share to Infant

Share to Infant, Newborn

Share to Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 28905428
DOI: 10.1111/ejh.12964

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cost-effective screening of DNMT3A coding sequence identifies somatic mutation in pediatric T-cell acute lymphoblastic leukemia.PMID 28905428Read ↗

Mutational analysis of DNMT3A gene in acute leukemias and common solid cancers.Semantic proximity Read ↗

Clinicopathologic Effect of DNMT3A Mutation in Adult T-Cell Acute Lymphoblastic Leukemia.Semantic proximity Read ↗

Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: a report from the Children's Oncology Group.Semantic proximity Read ↗

AML-Associated Mutations in DNA Methyltransferase DNMT3A.Semantic proximity Read ↗

Detection of high-frequency and novel DNMT3A mutations in acute myeloid leukemia by high-resolution melting curve analysis.Semantic proximity Read ↗

DNMT3A mutations in acute myeloid leukemia.Semantic proximity Read ↗

DNMT3A mutations are rare in childhood acute myeloid leukemia.Semantic proximity Read ↗

DNMT3A Mutations in Acute Myeloid LeukemiaSemantic proximity Read ↗

DNMT3A mutation is associated with increased age and adverse outcome in adult T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

Functional Analysis of DNMT3A DNA Methyltransferase Mutations Reported in Patients with Acute Myeloid LeukemiaSemantic proximity Read ↗

Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia.Semantic proximity Read ↗

Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.