Article
Clinicopathologic Effect of DNMT3A Mutation in Adult T-Cell Acute Lymphoblastic Leukemia.
Clinical lymphoma, myeloma & leukemia - 1 Jan 2016
Aref Salah, El Menshawy Nadia, El-Ghonemy Mohamed Sabry, Zeid Tarek Abou, El-Baiomy Mohamed Ali
Abstract excerpt
BACKGROUND: The present study aimed to determine the frequencies and clinicopathologic effect of a DNMT3A [DNA (cytosine-5)-methyltransferase 3A] mutation in patients with adult T-cell acute lymphoblastic leukemia (T-ALL). PATIENTS AND METHODS: A total of 64 patients with T-ALL who had been admitted to Mansoura University Oncology Center were included in the present study. For all patients, DNA extraction and...
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