Article
Critical roles of hMAGEA2 in induced pluripotent stem cell pluripotency, proliferation, and differentiation.
Cell biochemistry and function - 1 Oct 2017
Park Song, Sung Yonghun, Jeong Jain, Choi Minjee, Lee Jinhee, Kwon Wookbong, Jang Soyoung, Park Si Jun, Kim Jae Young, Kim Sung Hyun, Yoon Duhak, Ryoo Zae Young, Kim Myoung Ok
Abstract excerpt
Induced pluripotent stem (iPS) cells are important for clinical application and stem cell research. Although human melanoma-associated antigen A2 (hMAGEA2) expression is known to affect differentiation in embryonic stem cells, its specific role in iPS cells remains unclear. To evaluate the function of hMAGEA2 and its characteristics in iPS cells, we produced hMAGEA2-overexpressing iPS cells from...
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