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Article

Mutations in the prostate specific antigen (PSA/KLK3) correlate with male infertility.

Scientific reports - 11 Sept 2017

Gupta Nishi, Sudhakar Digumarthi V S, Gangwar Pravin Kumar, Sankhwar Satya Narayan, Gupta Nalini J, Chakraborty Baidyanath, Thangaraj Kumarasamy, Gupta Gopal, Rajender Singh

Abstract excerpt

Prostate specific antigen (PSA/KLK3) is known to be the chief executor of the fragmentation of semenogelins, dissolution of semen coagulum, thereby releasing sperm for active motility. Recent research has found that semenogelins also play significant roles in sperm fertility by affecting hyaluronidase activity, capacitation and motility, thereby making PSA important for sperm fertility beyond simple semen...

Read the complete abstract on PubMed

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Share to Amino Acid Substitution
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infertility, Male

Share to Kallikreins

Share to Polymorphism, Single Nucleotide

Share to Prostate-Specific Antigen

Share to Risk Assessment

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 28894123
DOI: 10.1038/s41598-017-10866-1
PMCID: PMC5593825

Genes

KLK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in the prostate specific antigen (PSA/KLK3) correlate with male infertility.PMID 28894123Read ↗

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