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Article

Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing.

Journal of visualized experiments : JoVE - 1 Sept 2017

Brooks Elliott P, Nichols James T

Abstract excerpt

Zebrafish mutant phenotypes are often incompletely penetrant, only manifesting in some mutants. Interesting phenotypes that inconsistently appear can be difficult to study, and can lead to confounding results. The protocol described here is a straightforward breeding paradigm to increase and decrease penetrance in lethal zebrafish skeletal mutants. Because lethal mutants cannot be selectively bred directly, the...

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Identifiers

PMID: 28892034
DOI: 10.3791/56200
PMCID: PMC5614404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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