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Article

Epidermal growth factor receptor as a therapeutic target in glioblastoma.

Neuromolecular medicine - 1 Jun 2013

Kalman B, Szep E, Garzuly F, Post D E

Abstract excerpt

Glioblastoma represents one of the most challenging problems in neurooncology. Among key elements driving its behavior is the transmembrane epidermal growth factor receptor family, with the first member epidermal growth factor receptor (EGFR) centered in most studies. Engagement of the extracellular domain with a ligand activates the intracellular tyrosine kinase (TK) domain of EGFR, leading to...

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Source

Identifiers

PMID: 23575987
DOI: 10.1007/s12017-013-8229-y

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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