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Article

Molecular pathologic diagnosis of epidermal growth factor receptor.

Neuro-oncology - 1 Oct 2014

Maire Cecile L, Ligon Keith L

Abstract excerpt

Epidermal growth factor receptor (EGFR) was one of the first oncogenes identified in glioblastoma (GBM) and remains one of the most attractive therapeutic targets. Genomic alterations in EGFR are present in 57% of patients and are strikingly diverse, including gene amplification, rearrangements, and point mutations. Each aberration class has important clinical implications for diagnosis, prognosis, or therapeutic...

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Identifiers

PMID: 25342599
DOI: 10.1093/neuonc/nou294
PMCID: PMC4207139

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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