Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional analysis of a vacuolar ABC transporter in wild-type Candida albicans reveals its involvement in virulence.

Molecular microbiology - 1 Feb 2002

Theiss Stephanie, Kretschmar Marianne, Nichterlein Thomas, Hof Herbert, Agabian Nina, Hacker Jörg, Köhler Gerwald A

Abstract excerpt

ATP-driven transport proteins belonging to the ATP-binding cassette (ABC) superfamily perform important functions in cell metabolism and detoxification. Compounds can be actively transported across membranes, including the plasma membrane or organellar membranes. The vacuole is an important organelle in fungal cells required for compartmentalization of metabolites as well as toxic substances. Sequestration into...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP-Binding Cassette Transporters
Share to Candida albicans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Candidiasis

Share to Gene Expression Regulation, Fungal

Share to Green Fluorescent Proteins

Share to Intracellular Membranes

Share to Luminescent Proteins

Share to Vacuoles

Source

Identifiers

PMID: 11929516
DOI: 10.1046/j.1365-2958.2002.02769.x

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional analysis of a vacuolar ABC transporter in wild-type Candida albicans reveals its involvement in virulence.PMID 11929516Read ↗

The ABCs of Candida albicans Multidrug Transporter Cdr1Semantic proximity Read ↗

Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicansSemantic proximity Read ↗

Mitochondrial Protease Oct1p Regulates Mitochondrial Homeostasis and Influences Pathogenicity through Affecting Hyphal Growth and Biofilm Formation Activities in Candida albicansSemantic proximity Read ↗

Host-Pathogen Interactions Mediated by MDR Transporters in Fungi: As Pleiotropic as it Gets!Semantic proximity Read ↗

Role of TFP1 in vacuolar acidification, oxidative stress and filamentous development in Candida albicans.Semantic proximity Read ↗

Recent advances on Candida albicans biology and virulenceSemantic proximity Read ↗

ABC Transporters in Saccharomyces cerevisiae and Their Interactors: New Technology Advances the Biology of the ABCC (MRP) SubfamilySemantic proximity Read ↗

Contribution of VMA5 to vacuolar function, stress response, ion homeostasis and autophagy in Candida albicans.Semantic proximity Read ↗

Tfp1 is required for ion homeostasis, fluconazole resistance and N-Acetylglucosamine utilization in Candida albicans.Semantic proximity Read ↗

Fungal ATP-binding cassette (ABC) transporters in drug resistance & detoxification.Semantic proximity Read ↗

Multidrug resistance in fungi: regulation of transporter-encoding gene expressionSemantic proximity Read ↗

A novel role of the vacuolar calcium channel Yvc1 in stress response, morphogenesis and pathogenicity of Candida albicansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.