Article
The association of HLA-DQB1*0602 but not HLA-DRB1*15 with obstructive sleep apnea.
Clinical and investigative medicine. Medecine clinique et experimentale - 29 Aug 2017
Momany Suleiman M, Al-Qatarneh Thamer A, Khader Yousef S, Abu-Harfeil Nizar M, Daoud Ammar K, Mahasneh Amjad A
Abstract excerpt
PURPOSE: Obstructive sleep apnea (OSA) is a sleep breathing disorder with unclear multifactorial pathogenesis. This study aimed to investigate the association between OSA and two human leukocyte antigens (HLA) alleles; DQB1*0602 and DRB1*15. METHODS: Forty patients with OSA and 40 control subjects were enrolled in the study. OSA diagnosis was made utilizing the Apnea-Hypopnea Index (AHI)≥5 in overnight...
Topics
- Adult
- Aged
- Alleles
- Female
- Genetic Predisposition to Disease
- HLA-DQ beta-Chains
- HLA-DRB1 Chains
- Humans
- Male
- Middle Aged
- Odds Ratio
