Article
Vascular endothelial growth factor genotypes and haplotypes contribute to the susceptibility of obstructive sleep apnea syndrome.
PloS one - 1 Jan 2014
Cao Chao, Ding Qunli, Lv Dan, Dong Zhe, Sun Shifang, Chen Zhongbo, Shen Huahao, Deng Zaichun
Abstract excerpt
BACKGROUND: To investigate whether VEGF polymorphisms (-460 T/C, +405 G/C, and +936 C/T)/haplotypes influence the susceptibility of obstructive sleep apnea (OSA). METHOD: A prospective case-control study was conducted to evaluate the genetic effects of VEGF polymorphisms on the development of OSA. 150 patients and 225 healthy controls were recruited for this study and their genotypes were determined by polymerase...
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