Article
HLA-DRB1 allele frequency and immunological response in obstructive sleep apnea syndrome in Turkish population.
The clinical respiratory journal - 1 Oct 2018
Tepebaşı Muhammet Yusuf, Şahin Calapoğlu Nilüfer, Öztürk Önder, Sancer Okan, Gonca Taner
Abstract excerpt
INTRODUCTION: Obstructive sleep apnea syndrome (OSAS) is a complex, polygenic and multifactorial disease. The relationship between Human Leukocyte Antigen (HLA) polymorphisms and sleep disturbances has been established, but the relationship with HLA alleles has not been fully clarified. In addition, sleep deprivation in OSAS patients can cause changes that affect the components and responses of the immune system....
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