Article
[Expression of HLA-DRB1*15 genotype in children with acquired aplastic anemia and its relation to effect of immunosuppressive therapy].
Zhongguo shi yan xue ye xue za zhi - 1 Dec 2007
Huang Yong-Lan, Huang Shao-Liang, Huang Ke, Bao Rong
Abstract excerpt
This study was purpose to investigate the frequency of HLA-DRB1*15 expression in children with aplastic anemia (AA) and its relation to effect of immunosuppressive therapy. HLA-DR genotypes were detected by SSP-PCR in 40 patients with acquired aplastic anemia and 107 normal controls, and the expressions of HLA-DR gene in AA patients and normal controls were compared. 32 out of 40 patients were treated with...
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