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Article

Mitochondrial mutations in human cancer: Curation of translation.

RNA biology - 2 Jan 2018

Caudron-Herger Maϊwen, Diederichs Sven

Abstract excerpt

As a genetic disease, cancer is caused by the activation of oncogenes and the inhibition of tumor suppressor genes via genetic and epigenetic mechanisms. Given the important role of energy metabolism in tumors, we analyzed the cancer-derived mutations occurring in the DNA of the mitochondrion. Mutations in the mitochondrial DNA (mtDNA) compared to nuclear DNA are 62% decreased relative to the coding length per...

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Identifiers

PMID: 28873329
DOI: 10.1080/15476286.2017.1373239
PMCID: PMC5785980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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