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Article

Mitochondrial mutations in cancer.

Oncogene - 7 Aug 2006

Brandon M, Baldi P, Wallace D C

Abstract excerpt

The metabolism of solid tumors is associated with high lactate production while growing in oxygen (aerobic glycolysis) suggesting that tumors may have defects in mitochondrial function. The mitochondria produce cellular energy by oxidative phosphorylation (OXPHOS), generate reactive oxygen specie...

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Identifiers

PMID: 16892079
DOI: 10.1038/sj.onc.1209607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16892079-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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