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Article

Pharmacogenetics of aldo-keto reductase 1C (AKR1C) enzymes.

Expert opinion on drug metabolism & toxicology - 1 Oct 2017

Alshogran Osama Y

Abstract excerpt

INTRODUCTION: Genetic variation in metabolizing enzymes contributes to variable drug response and disease risk. Aldo-keto reductase type 1C (AKR1C) comprises a sub-family of reductase enzymes that play critical roles in the biotransformation of various drug substrates and endogenous compounds such as steroids. Several single nucleotide polymorphisms have been reported among AKR1C encoding genes, which may affect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28871815
DOI: 10.1080/17425255.2017.1376648

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