Article
Genetic basis of drug metabolism.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists - 1 Nov 2002
Ma Margaret K, Woo Michael H, McLeod Howard L
Abstract excerpt
The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is discussed. Recent advances in pharmacogenomic research have begun to elucidate the inherited nature of interindividual differences in drug-induced adverse reactions, toxicity, and therapeutic responses. In one particular...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
