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Article

New Genetic Associations Between Alzheimer's Disease and Its Key Risk Factors.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society - 1 Sept 2026

Gholami Morteza, Ahmadi Ali Asghar, Niaki Mohammad Amin Akhavan, Asouri Mohsen, Saeedi Saeedeh, Amoli Mahsa M, Larijani Bagher

Abstract excerpt

INTRODUCTION: This study aimed to explore shared genetic architectures underlying Alzheimer's disease (AD) and its known risk factors. METHODS: Significant common variants between AD and its risk factors were identified using GWAS data. The 1000 Genomes Project genotyping data enabled the detection of linkage disequilibrium (LD) blocks and haplotype structures. Functional impact assessments, protein-protein...

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Identifiers

PMID: 42535978
DOI: 10.1111/psyg.70198
PMCID: PMC13426341

Genes

TOMM40
APOC1
APOE
ABCA1
APP
LRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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