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Article

Shared genetic etiology underlying Alzheimer's disease and type 2 diabetes.

Molecular aspects of medicine - 1 Jan 2000

Hao Ke, Di Narzo Antonio Fabio, Ho Lap, Luo Wei, Li Shuyu, Chen Rong, Li Tongbin, Dubner Lauren, Pasinetti Giulio Maria

Abstract excerpt

Epidemiological evidence supports the observation that subjects with type 2 diabetes (T2D) are at higher risk to develop Alzheimer's disease (AD). However, whether and how these two conditions are causally linked is unknown. Possible mechanisms include shared genetic risk factors, which were investigated in this study based on recent genome wide association study (GWAS) findings. In order to achieve our goal, we...

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Share to Alzheimer Disease
Share to Diabetes and associated disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Diet and metabolism studies

Share to Genetic Associations and Epidemiology

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 26116273
DOI: 10.1016/j.mam.2015.06.006
PMCID: PMC6021176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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