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Article

Evaluating the Causal Effect of Type 2 Diabetes on Alzheimer's Disease Using Large-Scale Genetic Data.

The journal of prevention of Alzheimer's disease - 1 Jan 2024

Liu D, Baranova A, Zhang F

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) has a high comorbidity with type 2 diabetes (T2D). However, there is still some controversy over whether T2D has a causal impact on AD at present. OBJECTIVES: We aimed to reveal whether T2D has a causal effect on AD using large-scale genetic data. METHODS: Firstly, we performed a primary two-sample Mendelian randomization (MR) analysis to assess the potential causal effects of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39350373
DOI: 10.14283/jpad.2024.148

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