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Article

Chronic Rapamycin Treatment Improved Metabolic Phenotype but Inhibited Adipose Tissue Browning in High-Fat Diet-Fed C57BL/6J Mice.

Biological & pharmaceutical bulletin - 1 Jan 2017

Wang Yan, He Zhi, Li Xianhui

Abstract excerpt

Rapamycin (Rap) has been demonstrated to affect lipid metabolism through stimulating lipolysis, inhibiting de novo lipogenesis and reducing adiposity. In the present study, we investigated rapamycin exposure's influence on adipose tissue browning in high-fat diet-induced fatty mice. Four-week old C57BL/6J mice were fed normal chow or high-fat diet for a period of 6 weeks and then divided into three groups: (1)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28867720
DOI: 10.1248/bpb.b16-00946

Genes

CIDEA
PGC
PRDM16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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