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Article

BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays.

PloS one - 1 Jan 2017

Mahmoud Abeer M, Macias Virgilia, Al-Alem Umaima, Deaton Ryan J, Kadjaksy-Balla Andre, Gann Peter H, Rauscher Garth H

Abstract excerpt

PURPOSE: Mutations in BRCA1 are associated with familial as well as sporadic aggressive subtypes of breast cancer, but less is known about whether BRCA1 expression or subcellular localization contributes to progression in population-based settings. METHODS: We examined BRCA1 expression and subcellular localization in invasive breast cancer tissues from an ethnically diverse sample of 286 patients and 36 normal...

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Identifiers

PMID: 28863181
DOI: 10.1371/journal.pone.0184385
PMCID: PMC5581176

Genes

BRCA1
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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