Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential expression and subcellular localization of murine BRCA1 and BRCA1-delta 11 isoforms in murine and human cell lines.

International journal of cancer - 15 Nov 2000

Bachelier R, Dalla Venezia N, Mazoyer S, Frappart L, Lenoir G M, Vincent A

Abstract excerpt

BRCA1 mutations are involved in breast and ovarian cancer predisposition in humans. The biological functions of the murine BRCA1 gene have been extensively studied but little is known about murine BRCA1 proteins. To better characterize these proteins, we have cloned the full-length murine BRCA1 cDNA and a splice variant deleted of exon 11, BRCA1-delta 11, by RT-PCR method. Three polyclonal antibodies raised...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3 Cells
Share to Alternative Splicing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to BRCA1 Protein

Share to Gene Library

Share to Genes, BRCA1

Share to Protein Isoforms

Share to Sequence Deletion

Share to Teratoma

Source

Identifiers

PMID: 11058866
DOI: 10.1002/1097-0215(20001115)88:4<519::aid-ijc2>3.0.co;2-r

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential expression and subcellular localization of murine BRCA1 and BRCA1-delta 11 isoforms in murine and human cell lines.PMID 11058866Read ↗

The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D.Semantic proximity Read ↗

A nuclear function for the tumor suppressor BRCA1.Semantic proximity Read ↗

Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci.Semantic proximity Read ↗

The functions of breast cancer susceptibility gene 1 (BRCA1) product and its associated proteins.Semantic proximity Read ↗

Aberrant subcellular localization of BRCA1 in breast cancer.Semantic proximity Read ↗

BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays.Semantic proximity Read ↗

BRCA1 is differentially expressed in human tumor cells.Semantic proximity Read ↗

Construction of a dual affinity tagged allele of the Rb1 tumor suppressor gene in the mouse.Semantic proximity Read ↗

Brca1 regulates in vitro differentiation of mammary epithelial cells.Semantic proximity Read ↗

Sequence analysis of the rat Brca1 homolog and its promoter region.Semantic proximity Read ↗

Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.Semantic proximity Read ↗

Dominant-negative activity of a Brca1 truncation mutant: effects on proliferation, tumorigenicity in vivo, and chemosensitivity in a mouse ovarian cancer cell line.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.