Article
The Functional Impact of Alternative Splicing in Cancer.
Cell reports - 29 Aug 2017
Climente-González Héctor, Porta-Pardo Eduard, Godzik Adam, Eyras Eduardo
Abstract excerpt
Alternative splicing changes are frequently observed in cancer and are starting to be recognized as important signatures for tumor progression and therapy. However, their functional impact and relevance to tumorigenesis remain mostly unknown. We carried out a systematic analysis to characterize the potential functional consequences of alternative splicing changes in thousands of tumor samples. This analysis...
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