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Article

Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method.

BMC medical genetics - 29 Aug 2017

Chen Guo-Bo, Lee Sang Hong, Montgomery Grant W, Wray Naomi R, Visscher Peter M, Gearry Richard B, Lawrance Ian C, Andrews Jane M, Bampton Peter, Mahy Gillian, Bell Sally, Walsh Alissa, Connor Susan, Sparrow Miles, Bowdler Lisa M, Simms Lisa A, Krishnaprasad Krupa, Radford-Smith Graham L, Moser Gerhard

Abstract excerpt

BACKGROUND: Predicting risk of disease from genotypes is being increasingly proposed for a variety of diagnostic and prognostic purposes. Genome-wide association studies (GWAS) have identified a large number of genome-wide significant susceptibility loci for Crohn's disease (CD) and ulcerative colitis (UC), two subtypes of inflammatory bowel disease (IBD). Recent studies have demonstrated that including only loci...

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Identifiers

PMID: 28851283
DOI: 10.1186/s12881-017-0451-2
PMCID: PMC5576242

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