Polygenic risk scores for Crohn's disease risk prediction in a Chinese population: insights from multi-ethnic genome-wide association studies.

Abstract excerpt

Crohn's disease (CD) is a chronic inflammatory bowel disease with a complex etiology involving genetic, immune, microbial, and environmental factors. Despite advances in understanding its pathogenesis, accurately predicting CD risk remains challenging, particularly in East Asian populations. In this study, we evaluated the performance of a polygenic risk score (PRS) model to predict CD risk in a Chinese cohort...

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• Asian People
• Case-Control Studies
• China
• Crohn Disease
• East Asian People