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Article

Sex Chromosome Complement Defines Diffuse Versus Focal Angiotensin II-Induced Aortic Pathology.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2018

Alsiraj Yasir, Thatcher Sean E, Blalock Eric, Fleenor Bradley, Daugherty Alan, Cassis Lisa A

Abstract excerpt

OBJECTIVE: Aortic pathologies exhibit sexual dimorphism, with aneurysms in both the thoracic and abdominal aorta (ie, abdominal aortic aneurysm [AAA]) exhibiting higher male prevalence. Women have lower prevalence of aneurysms, but when they occur, aneurysms progress rapidly. To define mechanisms for these sex differences, we determined the role of sex chromosome complement and testosterone on the location and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Dilatation, Pathologic

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Share to Sex-Determining Region Y Protein

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Source

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Identifiers

PMID: 29097367
DOI: 10.1161/ATVBAHA.117.310035
PMCID: PMC5864127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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