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Article

Tumor necrosis factor alpha polymorphisms are associated with Parkinson's disease age at onset.

Neuroscience letters - 29 Sept 2017

Lindenau Juliana D, Altmann Vivian, Schumacher-Schuh Artur F, Rieder Carlos R, Hutz Mara H

Abstract excerpt

The role of neuroinflammation in Parkinson's disease (PD) has been demonstrated through several different approaches. It was suggested an inflammation-derived oxidative stress and cytokine-dependent toxicity role in the nigrostriatal pathway degeneration and hasten progression of disease. Tumor necrosis factor alpha (TNFA) gene promoter polymorphisms might alter the expression of this cytokine contributing to the...

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Identifiers

PMID: 28844731
DOI: 10.1016/j.neulet.2017.08.049

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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