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Article

Genetic regulation of fatty acid content in adipose tissue.

American journal of human genetics - 5 Feb 2026

Yan Xinyu, Roberts Amy L, El-Sayed Moustafa Julia S, Villicaña Sergio, Al-Hilal Maryam, Tomlinson Max, Menni Cristina, Sanders Thomas A B, Freidin Maxim B, Bell Jordana T, Small Kerrin S

Abstract excerpt

Fatty acids are important as structural components, energy sources, and signaling mediators. While studies have extensively explored genetic regulation of fatty acids in serum and other bodily fluids, their regulation within adipose tissue, a crucial regulator of cardiovascular and metabolic health, remains unclear. Here, we investigated the genetic regulation of 18 fatty acids in subcutaneous adipose tissue from...

Topics

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Adipose Tissue
DNA Methylation
Fatty Acids
Gene Expression Regulation
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Quantitative Trait Loci

Subcutaneous Fat

Source

Open in PubMed Open full text

Identifiers

PMID: 41534528
DOI: 10.1016/j.ajhg.2025.12.008
PMCID: PMC13087407

Genes

ACSL3
ADAMTSL1
EXOC6B
FADS1
MKRN2
SCD
SNTB1
TSEN2
ZBTB41

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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