Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of a low expression haplotype in canine glutathione S-transferase (GSTT1) and its prevalence in golden retrievers.

Veterinary and comparative oncology - 1 Mar 2018

Craft S, Ekena J, Mayer B, Thamm D H, Saba C, Chun R, Trepanier L A

Abstract excerpt

Glutathione S-transferase-theta (GSTT1) is a carcinogen detoxification enzyme, and low activity variants are associated with lymphoma in humans. We recently found a variant in the 3' untranslated region (UTR) of canine GSTT1, *101_102insT, which was predicted to change miRNA binding and was found in 5 of 17 golden retriever (GR) dogs with lymphoma but none of 14 healthy GRs. The aim of this study was to determine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dog Diseases

Share to Glutathione Transferase

Share to Haplotypes

Share to Lymphoma

Source

Identifiers

PMID: 28840668
DOI: 10.1111/vco.12333

Genes

GSTT1
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of a low expression haplotype in canine glutathione S-transferase (GSTT1) and its prevalence in golden retrievers.PMID 28840668Read ↗

Positive association between a glutathione-S-transferase polymorphism and lymphoma in dogs.Semantic proximity Read ↗

A 6-bp Deletion Variant in a Novel Canine Glutathione-S-Transferase Gene (GSTT5) Leads to Loss of Enzyme Function.Semantic proximity Read ↗

Genetic and environmental risk for lymphoma in boxer dogs.Semantic proximity Read ↗

Glutathione S-transferase theta genotypes and environmental exposures in the risk of canine transitional cell carcinoma.Semantic proximity Read ↗

Polymorphism of glutathione S-transferase P1 of dogs with mammary tumours.Semantic proximity Read ↗

Impact of polymorphisms in the 5’-UTR of glutathione S-transferase P1 on proliferative activity in canine mammary tumoursSemantic proximity Read ↗

Glutathione-S-transferase-theta genotypes and the risk of cyclophosphamide toxicity in dogs.Semantic proximity Read ↗

Role of polymorphisms of GSTM1, GSTT1 and GSTP1 Ile105Val in Hodgkin and non-Hodgkin lymphoma risk: a Human Genome Epidemiology (HuGE) review.Semantic proximity Read ↗

Canine red blood cell thiopurine S-methyltransferase: companion animal pharmacogenetics.Semantic proximity Read ↗

Genome-wide association analysis of canine T zone lymphoma identifies link to hypothyroidism and a shared association with mast-cell tumors.Semantic proximity Read ↗

Gilbert syndrome redefined: a complex genetic haplotype influences the regulation of glucuronidation.Semantic proximity Read ↗

Clinical implications of glutathione S-transferase genotyping in patients with diffuse large B-cell lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.