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Article

Glutathione S-transferase theta genotypes and environmental exposures in the risk of canine transitional cell carcinoma.

Journal of veterinary internal medicine - 1 May 2019

Luethcke Katherine R, Ekena Joanne, Chun Ruthanne, Trepanier Lauren A

Abstract excerpt

INTRODUCTION: Transitional cell carcinoma (TCC) in humans is associated with environmental exposures and variants in glutathione S-transferase (GST) genes. Scottish Terriers have a high breed risk for TCC, but the relationship between genetic and environmental risk in dogs is not fully understood. HYPOTHESES: Scottish Terriers have a higher frequency of GST-theta variants compared to lower risk breeds. Dogs with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31008543
DOI: 10.1111/jvim.15504
PMCID: PMC6524089

Genes

GSTT1
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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