Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplasty.

doi:10.1186/s40001-017-0271-z

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplasty.

European journal of medical research - 23 Aug 2017

Stelmach Patrick, Kauther Max D, Fuest Lena, Kurscheid Gina, Gehrke Thorsten, Klenke Stefanie, Jäger Marcus, Wedemeyer Christian, Bachmann Hagen S

Abstract excerpt

BACKGROUND: Aseptic loosening is a main cause for revision surgery after total hip arthroplasty (THA) and there is no reliable marker for the early detection of patients at high risk. This study has been performed to validate association of the T393C polymorphism (rs7121) in the GNAS1 gene, encoding for the alpha-subunit of heterotrimeric G-protein Gs, with risk for and time to aseptic loosening after THA, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Arthroplasty, Replacement, Hip

Share to Case-Control Studies

Share to Chromogranins

Share to GTP-Binding Protein alpha Subunits, Gs

Share to Mutation, Missense

Share to Polymorphism, Single Nucleotide

Share to Postoperative Complications

Source

Open in PubMed Open full text

Identifiers

PMID: 28830502
DOI: 10.1186/s40001-017-0271-z
PMCID: PMC5568317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between GNAS1 T393C polymorphism and aseptic loosening after total hip arthroplasty.PMID 28830502Read ↗

Gender-dependent association of the GNAS1 T393C polymorphism with early aseptic loosening after total hip arthroplasty.Semantic proximity Read ↗

No Association of CALCA Polymorphisms and Aseptic Loosening after Primary Total Hip Arthroplasty.Semantic proximity Read ↗

Genetic susceptibility to aseptic loosening following total hip arthroplasty: a systematic review.Semantic proximity Read ↗

The Genetic Variations Associated With Time to Aseptic Loosening After Total Joint Arthroplasty.Semantic proximity Read ↗

Genetic susceptibility of early aseptic loosening after total hip arthroplasty: the influence of TIMP-1 gene polymorphism on Chinese Han population.Semantic proximity Read ↗

Genetic susceptibility to total hip arthroplasty failure: a case-control study on the influence of MMP 1 gene polymorphism.Semantic proximity Read ↗

[Genetic background of aseptic instability after total hip arthroplasty].Semantic proximity Read ↗

BCL2-938C>A and CALCA-1786T>C polymorphisms in aseptic loosened total hip arthroplasty.Semantic proximity Read ↗

Genetic susceptibility to aseptic loosening following total hip and knee arthroplasty: a systematic review of candidate-gene and genome-wide association studies.Semantic proximity Read ↗

The BCL2 -938C>A Promoter Polymorphism Is Associated with Risk for and Time to Aseptic Loosening of Total Hip Arthroplasty.Semantic proximity Read ↗

Aseptic loosening of total hip arthroplasty: preliminary genetic investigation.Semantic proximity Read ↗

Functional variants of the P2RX7 gene, aseptic osteolysis, and revision of the total hip arthroplasty: a preliminary study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.