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Article

No Association of CALCA Polymorphisms and Aseptic Loosening after Primary Total Hip Arthroplasty.

BioMed research international - 1 Jan 2018

Aydin-Yüce Tünay, Kurscheid Gina, Bachmann Hagen Sjard, Gehrke Thorsten, Dudda Marcel, Jäger Markus, Wedemeyer Christian, Kauther Max Daniel

Abstract excerpt

Studies of aseptic loosening showed an influence of calcitonin and α-CGRP, both encoded from the calcitonin/α-CGRP (CALCA) gene by alternative splicing. The aim of this study was to detect a possible association of the CALCA polymorphisms P1(rs1553005), P2(rs35815751), P3(rs5240), and P4(rs2956) with the time to aseptic loosening after THA. 320 patients suffering from aseptic loosening after primary total hip...

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Share to Aged
Share to Arthroplasty, Replacement, Hip
Share to Calcitonin Gene-Related Peptide
Share to Genetic Predisposition to Disease
Share to Genotype
Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 29967770
DOI: 10.1155/2018/3687415
PMCID: PMC6008809

Genes

CALCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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