Genetic susceptibility to total hip arthroplasty failure: a case-control study on the influence of MMP 1 gene polymorphism.

doi:10.1186/s13000-014-0177-9

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Genetic susceptibility to total hip arthroplasty failure: a case-control study on the influence of MMP 1 gene polymorphism.

Diagnostic pathology - 26 Sept 2014

Yan Yiguo, Hu Jianzhong, Lu Hongbin, Wang Wenjun

Abstract excerpt

BACKGROUND: Genetic factors plays an important role in early failure of total hip arthroplasty (THA) etiology and MMP-1 gene polymorphism rs5854 may be involved. The present study was conducted to reveal the possible association between MMP-1 rs5854 C/T polymorphism and the risk of early failure of THA (aseptic loosening). METHODS: The rs5854 single nucleotide polymorphism (SNP) in MMP-1 gene was genotyped in 63...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Arthroplasty, Replacement, Hip

Asian People

Case-Control Studies

China

Matrix Metalloproteinase 1

Risk Factors

Treatment Failure

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PMID: 25257555
DOI: 10.1186/s13000-014-0177-9
PMCID: PMC4180955

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