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Article

Genetic susceptibility of early aseptic loosening after total hip arthroplasty: the influence of TIMP-1 gene polymorphism on Chinese Han population.

Journal of orthopaedic surgery and research - 3 Dec 2014

Pan Fengyu, Hua Shan, Luo Yi, Yin Dongjun, Ma Zhuang

Abstract excerpt

OBJECTIVE: Genetic factor plays an important role in early failure of total hip arthroplasty (aseptic loosening) etiology, and TIMP-1 gene may be involved. The present study was conducted to reveal possible association between TIMP-1 polymorphisms with the risk of early failure of total hip arthroplasty (THA) (aseptic loosening). METHODS: The TIMP-1 single nucleotide polymorphisms (SNPs) rs4898, rs6609533, and...

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Identifiers

PMID: 25466591
DOI: 10.1186/s13018-014-0108-1
PMCID: PMC4324875

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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