[The relations between mutations of p53 anti-oncogene in atherosclerosis and levels of lipids in serum].

Abstract excerpt

OBJECTIVE: To further understanding the pathogenesis of human atherosclerosis, we studied the mutations of p53 anti-oncogene in Chinese atherosclerosis lesions and the relations between p53 gene mutations with the levels of serum lipoprotein and the contents of lipids in AS tissues. METHODS: p53 gene mutations were detected by a-32P-dCTP labelled radiative PCR-SSCP and the biochemical analyses of lipids in serum...

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