Article
Cancer biomarkers in human atherosclerotic lesions: no evidence of p53 involvement.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 1995
D'Agostini F, Fronza G, Campomenosi P, Izzotti A, Petrilli G L, Abbondandolo A, De Flora S
Abstract excerpt
In order to assess similarities between the atherogenic and the carcinogenic processes, we investigated whether the p53 tumor suppressor gene, the most commonly altered gene in human cancer, may be also involved in human atherosclerotic lesions. The medium layers of abdominal aorta fragments taken at surgery from 32 patients were subjected to immunohistochemical analysis, using either monoclonal (Pab 1801) or...
Topics
- Aged
- Aged, 80 and over
- Antibodies, Monoclonal
- Aorta, Abdominal
- Aortic Diseases
- Arginine
- Arteriosclerosis
- Base Sequence
- Biomarkers, Tumor
- Codon