Article
Risk Model for Prostate Cancer Using Environmental and Genetic Factors in the Spanish Multi-Case-Control (MCC) Study.
Scientific reports - 21 Aug 2017
Gómez-Acebo Inés, Dierssen-Sotos Trinidad, Fernandez-Navarro Pablo, Palazuelos Camilo, Moreno Víctor, Aragonés Nuria, Castaño-Vinyals Gemma, Jiménez-Monleón Jose J, Ruiz-Cerdá Jose Luis, Pérez-Gómez Beatriz, Ruiz-Dominguez José Manuel, Molero Jessica Alonso, Pollán Marina, Kogevinas Manolis, Llorca Javier
Abstract excerpt
Prostate cancer (PCa) is the second most common cancer among men worldwide. Its etiology remains largely unknown compared to other common cancers. We have developed a risk stratification model combining environmental factors with family history and genetic susceptibility. 818 PCa cases and 1,006 healthy controls were compared. Subjects were interviewed on major lifestyle factors and family history. Fifty-six PCa...
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