Article
Ergot alkaloids contribute to virulence in an insect model of invasive aspergillosis.
Scientific reports - 21 Aug 2017
Panaccione Daniel G, Arnold Stephanie L
Abstract excerpt
Neosartorya fumigata (Aspergillus fumigatus) is the most common cause of invasive aspergillosis, a frequently fatal lung disease primarily affecting immunocompromised individuals. This opportunistic fungal pathogen produces several classes of specialised metabolites including products of a branch of the ergot alkaloid pathway called fumigaclavines. The biosynthesis of the N. fumigata ergot alkaloids and their...
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