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Genetics, genomics and evolution of ergot alkaloid diversity.

Toxins - 14 Apr 2015

Young Carolyn A, Schardl Christopher L, Panaccione Daniel G, Florea Simona, Takach Johanna E, Charlton Nikki D, Moore Neil, Webb Jennifer S, Jaromczyk Jolanta

Abstract excerpt

The ergot alkaloid biosynthesis system has become an excellent model to study evolutionary diversification of specialized (secondary) metabolites. This is a very diverse class of alkaloids with various neurotropic activities, produced by fungi in several orders of the phylum Ascomycota, including plant pathogens and protective plant symbionts in the family Clavicipitaceae. Results of comparative genomics and...

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PMID: 25875294
DOI: 10.3390/toxins7041273
PMCID: PMC4417967

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