Article
Heterologous expression of lysergic acid and novel ergot alkaloids in Aspergillus fumigatus.
Applied and environmental microbiology - 1 Oct 2014
Robinson Sarah L, Panaccione Daniel G
Abstract excerpt
Different lineages of fungi produce distinct classes of ergot alkaloids. Lysergic acid-derived ergot alkaloids produced by fungi in the Clavicipitaceae are particularly important in agriculture and medicine. The pathway to lysergic acid is partly elucidated, but the gene encoding the enzyme that oxidizes the intermediate agroclavine is unknown. We investigated two candidate agroclavine oxidase genes from the...
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