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Article

The surveillance of colistin resistance and mobilized colistin resistance genes in multidrug-resistant Enterobacteriaceae isolated in Japan.

International journal of antimicrobial agents - 1 Jan 2022

Kawamoto Yasuhide, Kaku Norihito, Akamatsu Norihiko, Sakamoto Kei, Kosai Kosuke, Morinaga Yoshitomo, Ohmagari Norio, Izumikawa Koichi, Yamamoto Yoshihiro, Mikamo Hiroshige, Kaku Mitsuo, Oishi Kazunori, Yanagihara Katsunori

Abstract excerpt

BACKGROUND: The plasmid-mediated bacterial colistin-resistant gene, mcr, is of global concern in clinical healthcare. However, there are few reports of surveillance for mcr in Japan. The aim of this study was to assess the prevalence of colistin resistance by identifying nine mcr genes in extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae and carbapenem-resistant Enterobacteriaceae (CRE)...

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PMID: 34801675
DOI: 10.1016/j.ijantimicag.2021.106480

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