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Article

Phenotypic Heterogeneity of Circulating Tumor Cells Informs Clinical Decisions between AR Signaling Inhibitors and Taxanes in Metastatic Prostate Cancer.

Cancer research - 15 Oct 2017

Scher Howard I, Graf Ryon P, Schreiber Nicole A, McLaughlin Brigit, Jendrisak Adam, Wang Yipeng, Lee Jerry, Greene Stephanie, Krupa Rachel, Lu David, Bamford Pascal, Louw Jessica E, Dugan Lyndsey, Vargas Hebert A, Fleisher Martin, Landers Mark, Heller Glenn, Dittamore Ryan

Abstract excerpt

The heterogeneity of an individual patient's tumor has been linked to treatment resistance, but quantitative biomarkers to rapidly and reproducibly evaluate heterogeneity in a clinical setting are currently lacking. Using established tools available in a College of American Pathologists-accredited and Clinical Laboratory Improvement Amendments-certified clinical laboratory, we quantified digital pathology...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Prostatic Neoplasms, Castration-Resistant

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Source

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Identifiers

PMID: 28819021
DOI: 10.1158/0008-5472.CAN-17-1353
PMCID: PMC5666339

Genes

ARSI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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