Article
Inducible Knockout of Mouse Zfhx3 Emphasizes Its Key Role in Setting the Pace and Amplitude of the Adult Circadian Clock.
Journal of biological rhythms - 1 Oct 2017
Wilcox Ashleigh G, Vizor Lucie, Parsons Michael J, Banks Gareth, Nolan Patrick M
Abstract excerpt
The transcription factor zinc finger homeobox 3 (ZFHX3) plays a key role in coupling intracellular transcriptional-translational oscillations with intercellular synchrony in mouse suprachiasmatic nucleus (SCN). However, like many key players in central nervous system function, ZFHX3 serves an important role in neurulation and neuronal terminal differentiation while retaining discrete additional functions in the...
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